ZAP-X

ZAP-X Clinical

Brain

Ehret F, Kohlhase N, Eftimova D, Hofmann T, Fürweger C, Haidenberger A, et al. Self-shielding gyroscopic radiosurgery: A prospective experience and analysis of the first 100 patients. Cureus 2024;16:e56035. DOI: 10.7759/cureus.56035

Hendricks BK, DiDomenico JD, Barani IJ, Barranco FD. ZAP-X gyroscopic radiosurgery system: A preliminary analysis of clinical applications within a retrospective case series. Stereotac Funct Neurosurg 2022;100:99-107. DOI: 10.1159/000519862

Muacevic A, Eder MM, Hofmann T, Fürweger C, Ehret F. Self-shielding gyroscopic radiosurgery – A first clinical experience, case series, and dosimetric comparison. World Neurosurg 2022:164:e420-e426. DOI: 10.1016/j.wneu.2022.04.120

Pan L, Qu B, Bai J, Huang L, Wang J, Wang C, et al. The Zap-X radiosurgical system in the treatment of intracranial tumors: A technical case report. Neurosurgery 2021;88:E351-E355. DOI: 10.1093/neuros/nyaa550

Santacroce A, Muacevic A, Kohlhase N, Eftimova D, Hofmann T, Sammer, et al. Gyroscopic radiosurgery – Clinical experience and prospective analysis of over 500 treated tumors. World Neurosurg 2025;27:124684. DOI: 10.1016/j.wneu.2025.124684

ZAP-X Technology

Technology

Cao Q, Tan J, Ren Y, Xiong W, Wei X, Cheng W. Evaluation of radiation shielding requirements and self-shielding characteristics for a novel radiosurgery system. Health Phys 2021;121:506-512. DOI: 10.1097/HP.0000000000001465

Dosimetry

Pinnaduwage DS, Srivastava SP, Yan X, Jani SS, Jenkins C, Barani IJ, et al. Small-field beam data acquisition, detector dependency, and film-based validation for a novel self-shielded stereotactic radiosurgery system. Med Phys 2021;48:6121-6136. DOI: 10.1002/mp.15091

Souto C, Aguilar B, Dias V, Pascual E, Farinha G, Marcelino C, et al. Beam data commissioning, validation and clinical implementation of SRS gyroscopic system. Phys Med 2025; 133:104952. DOI: 10.1016/j.ejmp.2025.104952

Treatment planning

Srivastava SP, Jani SS, Pinnaduwage DS, Yan X, Rogers L, David F, et al. Treatment planning system and beam data validation for the ZAP-X: A novel self-shielded stereotactic radiosurgery system. Med Phys 2021;48:2494-2510. DOI: 10.1002/mp.14740