Glossary

BNCT now clinically convenient with SUMITOMO's cyclotron

BNCT now clinically convenient with SUMITOMO's cyclotron

Clinical trials show important patient benefits

BNCT: Boron Neutron Capture Therapy – boron reacts with thermal neutrons. The NeuCure BNCT-system by SHI has approval as medical device in Japan after several years of clinical trials. It is the only clinically operational commercial BNCT system today.

Bragg Peak: Dose peak at the end of the range of the charged particle beam. Used to optimize dose distribution of proton and light ion beams. More about Bragg Peak.

Cyclotron: Isochronous cyclotrons are designed to emit a steady particle beam with high energy and high current.

Dose distribution

Dose distribution

Only beams hitting the target are effective

ESS: Energy Selection System, also known as the Degrader, comprises of energy degrader and beam purification bend before the nozzle, which determines the energy i.e. depth of the Bragg Peak.

Fast pencil beam scanning

Fast pencil beam scanning

Accurate fast dose delivery from all angels

Gantry: Structure to rotate a beamline to allow ideally 360 degrees of treatment angles. The Gantry holds bending magnets and nozzle to deliver radiation precisely.

IMT: Integrated Medical Technologies Inc. makes good phantoms and QA tools. See Standard Imaging.

LIONESS: Light Ion Energy Selection System – Energy selection system for charged  particles from a cyclotron which adjusts range of different light ion beams’ Bragg Peak.

See what you treat

See what you treat

Dose Escalation is possible and safe when visibility is really good

Light Ions: In particle therapy.

MeV: Kinetic energy measured in MegaelectronVolts.

MR-Linac: Combining 8 FPS MR cine during treatments with sharp radiation beams, the MRIdian Linac from ViewRay is used to treat moving targets in critical locations with high doses.

NEUCURE: First and only commercially available (in Japan) clinical BNCT product consist of a cyclotron accelerator and beryllium target from Sumitomo, boron compound for injection by Stella Pharma, and RayStation TPS from Raysearch.

Maximize dose to target, minmimize dose to surrounding healthy tissue

Maximize dose to target, minmimize dose to surrounding healthy tissue

Greater precision leads to better cures and fewer complications

OAR: Organs At Risk – Avoidance structures in treatment planning.

Different radiation

Different radiation

Alpha, Gamma, X-rays/photons, neutrons, protons, helium

Photons/X-Rays, are used in conventional radiotherapy with linear accelerators.

Protons, Proton Therapy is a specialized sub-discipline of radiation therapy and radiosurgery, offering the dosimetric advantages of the Bragg Peak

Proton Pioneers

Proton Pioneers

PSI: Paul Scherrer Institute in Villigen near Zurich, Switzerland.

Quality Assurance and Quality Control

Quality Assurance and Quality Control

Missing the target is not an option. Doublecheck!

QA and QC: Rigorous Quality Assurance and Quality Control are key to accurate and safe delivery of tumoricidal radiation doses. The phantoms from IMTQA do a great job as pseudo patients for end to end verification of dose deliveries.

Singularily superior superconducting systems

Singularily superior superconducting systems

SUMITOMO also makes the cryocoolers for major medical magnets

SOBP: Spread Out Bragg Peak achieved by superposition of proton beams with varying energy.

SRS: Stereotactic radiosurgery of the brain, head and neck. High precision, high dose, single fraction or few fractions.

Superconducting: Superconducting magnets are cooled with Sumitomo cryocoolers. Most MRi’s and superconducting accelerators use SHI cryocoolers.

Short but loaded

Short but loaded

3 letters with meaning

TSL – The Svedberg Laboratory: Research particle accelerator at Uppsala University 1951-2016. The  first animal experiments with stereotactic radiosurgery, and the first human cancer treatments with proton therapy were performed at the Svedberg Laboratory using the  Gustav Werner cyclotron in 1957.

TLA – Three Letter Acronym: TSL, SRS, ESS, MRL, PSI, TPS, ZAP, SHI, OIS, OAR, MeV,MRI, PET, CIA, FBI, FAQ. LMT (Lioness Medtech), TSS.

TSS – Training Support Specialists: Clinical and technical specialist training ensures smooth and efficient ramp-up and operations of your new precision radiation technology.

SMART DOSE DISTRIBUTIONS

SMART DOSE DISTRIBUTIONS

MONTE CARLO TREATMENT PLANNING

TPS: Treatment Planning System is the computerized calculation of the dose distribution and development of treatment technique and strategy. Based on CT and MRI images and dose optimization and calculation algorithms.

Modern Radiosurgery

Modern Radiosurgery

No vault, no cobalt

ZAP-X: Futuristic self-shielded new radiosurgery system with 3 MV linac. Design to spread radiosurgery to benefit more patients.